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Clinical Trials in Israel / NCT05513846
Active, not recruiting Observational

Brain Age and Sleep Architecture in Meditators

NCT05513846 · tracked via the Priya Life Science Israel tracker
Sponsor
Beth Israel Deaconess Medical Center
Phase
Observational
Started
2022-11-10
Last updated
2026-09-30

Condition(s) studied

Brain Age

Investigational drug(s) / intervention(s)

DREEM EEG DeviceSleepImage Ring

DREEM EEG Device: The DREEM EEG device will be used to measure brain age.

SleepImage Ring: The SleepImage ring uses plethysmography to analyze sleep architecture and cardiopulmonary coupling.

Study summary

This is a single-center, cross-sectional study that will recruit approximately fifty seven (57) meditators and fifty one (51) controls. Individuals that have learned at least the Shambhavi Mahamudra Kriya practice and live in Massachusetts will be mailed a DREEM EEG device, and a sleepimage ring. Participants will be asked to wear the two devices while sleeping for three consecutive weekday nights (Sunday night to Thursday night) and two weekend nights (Friday and Saturday nights). While meditating during the day, participants will only wear the DREEM EEG headband. Participants will also undergo neurocognitive tests from the NIH toolbox during one virtual visit via video call. Meditators who join the study will be asked to invite a control subject to the study, matched for age and comorbidities.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria (Meditators): 1. Previous experience with learning Shambhavi Mahamudra Kriya 2. Age 18 years or older. 3. Lives in the United States barring California Inclusion Criteria (Controls): 1. Age 18 years or older 2. Lives in the United States barring California Exclusion Criteria (both groups): 1. Non-English Speaking 2. Night Shift workers

Primary outcome measure(s)

  • Sleep Architecture - DREEM EEG — Measured across 5 nights (3 weekday and 2 weekend nights) during the data collection period.
    Sleep architecture will be assessed using overnight DREEM EEG recordings. Measures will include including total sleep time, sleep efficiency, and sleep stage duration. Measures will be aggregated across available high-quality recordings for each participant.
  • Brain Age — Measured for 3 weekday and 2 weekend nights during the data collection period
    Brain Age will be calculated using an algorithm from the sleeping EEG. A Brain Age index score will be created for each participant based on an aggregate of the five days of sleeping EEG data. The Brain Age Index is the brain age calculated from the algorithm subtracted by the chronological age of the participant.
  • Sleep Measures - SleepImage Ring — Measured across 5 nights (3 weekday and 2 weekend nights).
    Sleep and cardiopulmonary measures will be assessed using the SleepImage Ring.
  • Cognitive Function — Assessed once during the study period.
    Cognitive function will be assessed using the NIH Toolbox Cognition Battery: Picture Vocabulary, List Sorting Working Memory, Picture Sequence Memory, and Oral Reading Recognition Tests.
  • Emotion — Assessed once during the study period.
    Emotional and psychosocial functioning will be assessed using the NIH Toolbox Emotion Battery: Positive Affect, General Life Satisfaction, Emotional Support, Instrumental Support, Friendship, Loneliness, and Perceived Stress measures.

Trial sites (1)

FacilityCityRegionStatus
Beth Israel Deaconess Medical Centre Boston Massachusetts

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05513846 on ClinicalTrials.gov ↗ ← All trials in Israel