EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis

Inclusion Criteria: 1. 65 years of age or older 2. Severe aortic stenosis 3. Patient is asymptomatic 4. LV ejection fraction ≥ 50% 5. Society of Thoracic Surgeons (STS) risk score ≤ 10 6. The study patient has been informed of the nature of the study, agrees to its provisions and has provided written informed consent. Exclusion Criteria: 1. Patient is symptomatic 2. Patient has any concomitant valvular, aortic, coronary artery disease requiring surgery making AVR a Class I indication. 3. Native aortic annulus size unsuitable for sizes 20, 23, 26, or 29 mm THV 4. Iliofemoral vessel characteristics that would preclude safe placement of the introducer sheath. 5. Left ventricular outflow tract calcification that would increase the risk of annular rupture or significant paravalvular leak post TAVR 6. Evidence of an acute myocardial infarction ≤ 30 days before randomization 7. Aortic valve is unicuspid, bicuspid with unfavorable features for TAVR, or is non-calcified 8. Severe aortic regurgitation (\>3+) 9. Severe mitral regurgitation (\>3+) or ≥ moderate mitral stenosis 10. Pre-existing mechanical or bioprosthetic valve in any position 11. Symptomatic carotid or vertebral artery disease or successful treatment of carotid stenosis within 30 days of randomization 12. Leukopenia, anemia, thrombocytopenia, history of bleeding diathesis or coagulopathy, or hypercoagulable states 13. Hemodynamic or respiratory instability requiring inotropic support, mechanical ventilation or mechanical heart assistance within 30 days of randomization 14. Hypertrophic cardiomyopathy with obstruction 15. Cardiac imaging evidence of intracardiac mass, thrombus or vegetation 16. Inability to tolerate or condition precluding treatment with anti-thrombotic therapy 17. Stroke or transient ischemic attack within 90 days of randomization 18. Renal insufficiency and/or renal replacement therapy 19. Active bacterial endocarditis within 180 days of randomization 20. Severe lung disease or currently on home oxygen 21. Severe pulmonary hypertension 22. History of cirrhosis or any active liver disease 23. Significant frailty as determined by the Heart Team 24. Significant abdominal or thoracic aortic disease that would preclude safe passage of the delivery system 25. Patient refuses blood products 26. BMI \>50 kg/m2 27. Estimated life expectancy \<24 months 28. Absolute contraindications or allergy to iodinated contrast that cannot be adequately treated with pre-medication 29. Currently participating in an investigational drug or another device study. 30. Active SARS-CoV-2 infection (Coronavirus-19 \[COVID-19\]) or previously diagnosed with COVID-19 with sequelae that could confound endpoint assessments