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Clinical Trials in France / NCT07660484
Starting soon Not applicable

Link Between ASCorbemia Level and Osteoporosis

NCT07660484 · tracked via the Priya Life Science France tracker
Sponsor
Centre Hospitalier Universitaire de Nice
Phase
Not applicable
Started
2026-07-01
Last updated
2026-06-22

Condition(s) studied

OsteoporosisVitamin C DeficiencyVertebral Fractures

Investigational drug(s) / intervention(s)

Plasma vitamin C assessment

Plasma vitamin C assessment: Blood sampling for measurement of plasma vitamin C concentration (ascorbemia) in patient of the study

Study summary

This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis. Forty participants will be enrolled at the Rheumatology

Eligibility

Sex
ALL
Min age
50 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Men aged 50 yars or older ; * Postmenopausal women ; * Afilliated with a health insurance and system ; * Written informed consent obtained. * Group 1 : Clincal osteoporotic vertebral fracture confirmed by imaging within the previous month ; Followed in the Rheumatology department for management of vertebral fracture. * Group 2 : Densitometric osteoporosis (T-score ≤ -2.5) ; No history of severe osteoporotic fracture ; No history of clinical or morphometric vertebral fracture. Exclusion Criteria: * Legal protection measure (guardianship, curatorship); * inability to provide informed consent ; * refusal to participate ; * Vertebral fracture related to tumor, * infection, trauma or non osteoporotic causes ; * asymptomatic vertebral fracture discovered incidentally ; * Severe densitometric osteoporosis for group 2 ; * Previous severe osteoporotic fracture for group B.

Primary outcome measure(s)

  • Plasma vitamin C concentration — day 1
    Comparison of plasma vitamin C concentration (ascorbemia, µmol/L) between patients with osteoporotic vertebral fractures and patients with osteoporosis without vertebral fracture.

Trial sites (1)

FacilityCityRegionStatus
CHU de Nice Nice France

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Other trials for the same condition

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RESTORE - Study of AGN1 LOEP to Prevent Secondary Hip Fractures Recruiting
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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07660484 on ClinicalTrials.gov ↗ ← All trials in France