Titration of Positive End-expiratory Pressure: Comparison Between Manual Thoracic or Abdominal Compression and Electrical Impedance Tomography

Condition(s) studied

Investigational drug(s) / intervention(s)

PEEP titrations: Assessment of ideal PEEP using electrical impedance tomography will be performed. The evaluation of PEEP using the thorax compression maneuver method will be carried out. A blood sample (the "blood gases") will be taken at the ideal PEEP determined by electrical impedance tomography and at the ideal PEEP determined by the manual chest compression maneuver.

Study summary

Patients with acute respiratory distress syndrome are placed on mechanical ventilation, and the adjustment of ventilator parameters is an important step in their care, in particular positive expiratory pressure, applied at the end of breathing.

The goal of this study is to learn if continuous anterior chest compression works as well as electrical impedance tomography for positive expiratory pressure titration.

Researchers will compare the two methods for each patient, in a randomly determined order : continuous anterior chest compression and electrical impedance tomography.

Participants will :

* have a pep titration with both techniques
* be included in the study for 28 days

Eligibility

Primary outcome measure(s)

• PEPCTAC — Day 0
  PEPCTAC (unit : cmH2O)
• PEPCAC — Day 0
  PEPCAC (unit : cmH2O)
• PEPEIT — Day 0
  PEPEIT (unit : cmH2O)

Trial sites (2)

More Centre Hospitalier Saint Joseph Saint Luc de Lyon trials in France

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