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Clinical Trials in France / NCT07524088
Recruiting Not applicable

Contamination of Young Children Hair During Acute Cannabis Intoxication

NCT07524088 · tracked via the Priya Life Science France tracker
Sponsor
University Hospital, Toulouse
Phase
Not applicable
Started
2026-07-31
Last updated
2026-09-21

Condition(s) studied

Cannabis Intoxication in Children

Investigational drug(s) / intervention(s)

sudoral and hairing sampling

sudoral and hairing sampling: Sweat sampling using the "sweat test" method, performed after skin stimulation with pilocarpine and a low electrical stimulation. Hair sampling during the follow-up consultation. Sweat, and capillary assays of THC and its main metabolites

Study summary

Hair analysis in pediatric cannabis intoxication is limited by possible sudoral self-contamination, especially in young children due to hair porosity. However, adult studies show no THC-COOH in sweat, challenging this hypothesis. THC-COOH presence in sweat has to this day never been studied in young children. Its absence would help assess the reliability of hair testing for prior exposure. Thus, our main objective is to describe whether THC-COOH can be detected in sweat following cannabis intoxication using gold standard techniques.

Eligibility

Sex
ALL
Min age
3 Months
Max age
3 Years
Healthy volunteers
No
Inclusion Criteria: * Child admitted to the Specialized Emergency Pole (POSU) and pediatric medico-surgical emergencies for acute cannabis intoxication. * Child older than 3 months and younger than 3 years. * Holders of parental authority, affiliated with or beneficiaries of a social security system. Exclusion Criteria: * History of cannabis intoxication identified during the interview and/or consultation of the medical record. * Contraindication to sweat sampling (described in section 6). * Absence of hair and/or hair length \< 1 cm at the time of inclusion. * Ongoing breastfeeding (exclusive and mixed). * Inability to provide study-related informations to the holders of parental authority.

Primary outcome measure(s)

  • Acide 11-nor-9-carboxy-THC (THC-COOH) concentrations in sweat collected during the first 24 hours following emergency admission. — Day 1
    concentration measured in sudoral sample (in µg/l)

Trial sites (1)

FacilityCityRegionStatus
Centre Hospitalier Universitaire Toulouse France Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07524088 on ClinicalTrials.gov ↗ ← All trials in France