Evolution of Masticatory Function, Orofacial Functions and Quality of Life of Patients Treated for Cancers of the Upper Aerodigestive Tract, Rehabilitated by Maxillofacial Prostheses.

NCT07471451 · tracked via the Priya Life Science France tracker

Sponsor

University Hospital, Clermont-Ferrand

Phase

Not applicable

Started

2026-05-20

Last updated

2026-07-07

Condition(s) studied

Head and Neck Cancer

Investigational drug(s) / intervention(s)

Prosthetic oral rehabilitation

Prosthetic oral rehabilitation: Prosthetic oral rehabilitation to restore oral function in patients with a history of upper aerodigestive tract cancer.

Study summary

This is a follow-up study of masticatory function, orofacial functions, and quality of life in patients with a history of upper aerodigestive tract cancer who have undergone rehabilitation with maxillofacial prostheses. The main objective of this study is to evaluate changes in masticatory function during a prosthetic rehabilitation program in patients with a history of upper aerodigestive tract cancer.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Adult patient who has given their consent * Patient with a history of upper aerodigestive tract cancer * Cooperative patient * Patient affiliated with a Social Security scheme * Patient capable of understanding and participating in the study * Patient not allergic to the foods being tested Exclusion Criteria: * Minors * Patients treated in the maxillofacial prosthetics clinic of the Odontology Department at Estaing University Hospital in Clermont Ferrand who do not require prosthetic rehabilitation * Patients who are unwilling to participate in the study, particularly in attending the various follow-up sessions * Patients who do not have a good command of written and spoken French * Patients under guardianship, curatorship, or judicial protection * Pregnant or breastfeeding patients * Patients receiving enteral or parenteral nutrition * Patients who have been diagnosed with a recurrence of their cancer and whose prognosis is life-threatening. * Patients with cognitive impairment

Primary outcome measure(s)

Particle size distribution of food bolus collected at the swallowing threshold — Baseline (T0) ; T1 (T0 + 3 months) ; T2 (T0 + 1 year)
Particle size distribution of food bolus collected at the swallowing threshold for raw carrot samples (CAR), objectified by the D50 value : median value of the particle size of each food bolus

Trial sites (1)

Facility	City	Region	Status
CHU de Clermont-Fd	Clermont-Ferrand	France	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07471451 on ClinicalTrials.gov ↗ ← All trials in France