Panniculitis in Dermatomyositis

Condition(s) studied

Study summary

Adipose tissue involvement is rare in dermatomyositis. The occurrence of partial or diffuse lipodystrophy is a rare but well-characterized manifestation, particularly in juvenile forms of dermatomyositis. Panniculitis, on the other hand, is exceptional and rarely described in the literature, mostly in the form of clinical cases.

Panniculitis in dermatomyositis is exceptional. There are no validated diagnostic criteria or treatment recommendations. Treatment is based, by analogy, on the therapeutic strategy for lupus panniculitis and involves synthetic antimalarials combined with steroids and/or immunosuppressants.

The aim of this study is to describe panniculitis in dermatomyositis in order to determine whether there are clinical or histological characteristics that distinguish it from other causes of panniculitis, particularly panniculitis associated with lupus erythematosus.

Eligibility

Primary outcome measure(s)

• Determine the clinical and histological characteristics of panniculitis in dermatomyositis — Up to 30 months
  The investigators aim to describe: how inflammation of the subcutaneous fat manifests * in individuals with dermatomyositis * both: * clinically and visually in the patient * under the microscope (histology)

Trial sites (1)

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