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Clinical Trials in France / NCT07334457
Recruiting Observational

Study of Platelet Population Changes Under Circulatory Support With ECMO

NCT07334457 · tracked via the Priya Life Science France tracker
Sponsor
University Hospital, Strasbourg, France
Phase
Observational
Started
2025-03-11
Last updated
2026-01-12

Condition(s) studied

Cardiac FailureRespiratory Failure

Study summary

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital. * Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours. Exclusion Criteria: * Subject who has expressed their opposition to participating in the study. * Subject under legal protection. * Subject under guardianship or curatorship.

Primary outcome measure(s)

  • Proportional Changes in the Different Platelet Populations (native, proaggregating, procoagulant, or apoptotic) — Days 1, 3, and 7 after the initiation of ECMO treatment.
    Proportional Changes in the Different Platelet Populations (native, proaggregating, procoagulant, or apoptotic) on Days 1, 3, and 7 after the initiation of ECMO treatment.

Trial sites (1)

FacilityCityRegionStatus
Service d'anesthésie-réanimation - CHU de Strasbourg - France Strasbourg France Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07334457 on ClinicalTrials.gov ↗ ← All trials in France