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Recruiting Observational

Evaluation of the PERC Score and the YEARS Algorithm in the Diagnosis of Pulmonary Embolism in the Emergency Department

NCT07313501 · tracked via the Priya Life Science France tracker
Phase
Observational
Started
2025-02-26
Last updated
2026-01-02

Condition(s) studied

Pulmonary Embolism

Study summary

The current diagnostic strategy for pulmonary embolism relies on clinical evaluation, followed by D-dimer testing and chest CT angiography. However, this approach leads to overuse of CT angiography. Diagnosis remains complex, with nonspecific clinical signs. Recent studies have explored new algorithms, such as the YEARS algorithm and the PERC score, which aim to support the diagnosis and reduce the need for imaging examinations. Their use could decrease waiting times in the emergency department and limit the need for additional investigations.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Adult patient (≥18 years) * Patient admitted to the adult emergency department of the Strasbourg University Hospital over a 6-month period (January to June 2024), for whom a D-dimer test and chest imaging (thoracic CT angiography or ventilation/perfusion scintigraphy) were performed Exclusion Criteria: \- No D-dimer test or test performed for another indication, no chest imaging (CT angiography or scintigraphy), long-term anticoagulant treatment.

Primary outcome measure(s)

  • Number of patients who would not have required imaging if the PERC score and YEARS algorithm criteria had been applied — Up to 12 months

Trial sites (1)

FacilityCityRegionStatus
Service d'Urgences Médico-Chirurgicales Adules - CHU de Strasbourg - France Strasbourg France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07313501 on ClinicalTrials.gov ↗ ← All trials in France