Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care

Condition(s) studied

Investigational drug(s) / intervention(s)

Capillary CRP: CRP measured semi-quantitatively using ACTIM-CRP device

Study summary

Fever is the leading reason for outpatient consultations among children aged 2 to 9 years. The main concern in fever is severe bacterial infection, particularly for younger children. History and clinical examination do not always differentiate viral infections from bacterial infection. In 20% of febrile children, no infectious focus is found after examination and additional tests are necessary. The first one is measuring C-reactive protein (CRP). The results are obtained in several hours on an outpatient basis, causing long delays before starting treatment and often requiring telephone calls or further consultations. Emergency room use is constantly increasing, generating growing tensions within healthcare facilities, yet a large number of visits are avoidable. Among children visiting the pediatric emergency room, parents reported being referred by their primary care physician in approximately 20% of cases for children aged 1 to 5 years and in 30% of cases for children under one year old. The use of capillary medical device to measure CRP in primary care could reduce this referral rate and help relieve overcrowding in emergency rooms, as well as unscheduled consultation centers and medical analysis laboratories. This would result in a streamlined care pathway, saving time for both physicians and patients, as well as reducing the cost of care for the healthcare system.

Eligibility

Primary outcome measure(s)

• Referral rates to any facility equipped for emergency laboratory testing between conditions — Day 1
  Referral: Yes/No as reported by the physician
• Referral rates to any facility equipped for emergency laboratory testing between conditions — Day 7
  Referral: Yes/No as reported by the parents

Trial sites (37)

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