Ireland
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Recruiting Observational

Comparing Montiroing Cardiac Index by Transpulmonary Thermodilution and Transesophageal Echocardiography During Liver Transplantation

NCT06899867 · tracked via the Priya Life Science France tracker
Phase
Observational
Started
2023-11-27
Last updated
2025-03-28

Condition(s) studied

Liver Transplantation

Investigational drug(s) / intervention(s)

Measure of cardiac index with thermodilution and transesophageal echocardiographySurgical anastomosis echography

Measure of cardiac index with thermodilution and transesophageal echocardiography: At 4 times of surgery, end-expiratory occlusion (EEO) test and measure of cardiac index before and after test with ETO and thermodilution

Surgical anastomosis echography: Visualisation of surgical anastomosis through transesophageal echocardiography : stenosis, doppler velocity, collar diameter

Study summary

Liver transplantation poses challenges due to hemodynamic changes throughout different surgical phases. Monitoring devices are essential for therapeutic adjustments. Transpulmonary thermodilution and transesophageal echocardiography are commonly used, but thermodilution may have limitations depending on the surgery.

This study aims to compare cardiac index variations between thermodilution and transesophageal echocardiography during liver transplantation. Patients undergo monitoring with both techniques. Measurements are recorded and reported at multiple time points.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * liver transplantation * adults Exclusion Criteria: * \- Oesophageal varice ligation \< 14 days * Mediastinal radiotherapy * Femoral bypass * Severe lower extremity artery disease

Primary outcome measure(s)

  • Cardiac index variation measured by thermodilution compared with transesophageal echography — At 4 times of surgery: after starting anesthesia, anhepatic phase, reperfusion and surgical anastomosis of biliary ducts. Data reported : - Cardiac Index before and after end-expiratory test. - Transoesophageal echography measurement of cardiac function

Trial sites (1)

FacilityCityRegionStatus
Croix Rousse Hsopital France Lyon Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06899867 on ClinicalTrials.gov ↗ ← All trials in France