Data collection: Retrospective pseudo-anonymized clinical and scannographic data from the routine management of patients in rhino-sinusology consultations.
Study summary
Chronic Nasal obstruction (CNO) is not currently measurable objectively because clinicians use validated declarative self-questionnaires whose results are linked to the level of understanding, the acute or chronic clinical situation, fatigue, psychological state and the desired gain. Using numerical simulations of the passage of air in the nasal cavities determining specific airflow parameters, the respiratory comfort of healthy subjects and the CNO of patients treated for this pathology could be explained.
Eligibility
Sex
ALL
Min age
18 Years
Max age
69 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* 18 years ≤ age \< 70 years
* BMI \< 30 kg/m2
* Subject or Patient of Caucasian ethnic origin or from the Mediterranean region.
* Asymptomatic subject with or without a septal deviation without sinonasal disease with a NOSE score ≤ 7 Or Patient suffering from chronic nasal obstruction of morphological origin (symptomatic septal or nasoseptal deviation) requiring surgical management with a NOSE score ≥ 9/20, without or .with sleep apnea with an Apnea-hypopnea index ≤ 20 with no other cause than this apnea syndrome
Exclusion Criteria:
* Acute or chronic rhinosinusitis with or without polyps (except controlled allergic rhinitis)
* Vasculitis
* Empty nasal cavity syndrome
* Septal perforations
* History of nasal plastic surgery, sinonasal endoscopic surgery and cancer with head or neck radiotherapy
* Uncontrolled bronchopulmonary pathology
* Treatments with nasal vasomotor repercussions.
Primary outcome measure(s)
Correlation coefficient — at inclusion (day 0) Correlation coefficient of at least one of the simulation parameters greater than 0.5 with the NOSE score in a healthy population and a pathological population. This parameter could be Pressure (P), Temperature (T), mass exchanges (C) and/or shear stresses (SS).
Trial sites (1)
Facility
City
Region
Status
CHU de Bordeaux
Bordeaux
France
Recruiting
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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