Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology
Condition(s) studied
Investigational drug(s) / intervention(s)
Saliva sample: Saliva sample
Study summary
GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological pathologies by analyzing of coding and non-coding RNA contained in patients saliva.
The study population consists of patients with clinically symptomatic females with one or more of the gynecological pathologies (endometriosis, adenomyosis, ovarian cysts, fibroids, ovarian/cervical/uterine cancer) and asymptomatic females.
The patients concerned by the study will be managed without modification of the care pathway, nor modification of the therapeutic indications, nor modification of the diagnostic or follow-up examinations necessary according to the context, which are carried out according to the local recommendations.
Eligibility
Primary outcome measure(s)
- Area under the curve (AUC) of the Receiver Operating Curve (ROC) — Through the end of study inclusions, an average of 1 year
Identify a diagnostic signature for each pathology (Endometriosis / Adenomyosis / Ovarian cysts / Fibroids / Cervical Displasia / Ovarian cancer / Cervical cancer /Uterine cancer) by analyzing of coding and non-coding RNA contained in the saliva.
Trial sites (13)
| Facility | City | Region | Status |
|---|---|---|---|
| CHU d'Angers | Angers | France | Not Yet Recruiting |
| Clinique Tivoli Ducos - IFEMENDO | Bordeaux | France | Recruiting |
| Institut Bergonié | Bordeaux | France | Not Yet Recruiting |
| CHU Caen | Caen | France | Recruiting |
| CGFL | Dijon | France | Not Yet Recruiting |
| CHU Lyon Sud | Lyon | France | Not Yet Recruiting |
| American Hospital of Paris | Neuilly-sur-Seine | France | Not Yet Recruiting |
| CHU de Rennes Site Hôpital Sud | Rennes | France | Not Yet Recruiting |
| Clinique La sagesse | Rennes | France | Not Yet Recruiting |
| CHU Rouen | Rouen | France | Recruiting |
| Clinique Pasteur | Toulouse | France | Recruiting |
| CHU Bretonneau-Tours | Tours | France | Recruiting |
| Institut Gustave Roussy | Villejuif | France | Not Yet Recruiting |
More ZIWIG trials in France
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06392997 on ClinicalTrials.gov ↗ ← All trials in France