Clinical Trials in France / NCT06244433
Recruiting
Observational
Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome
NCT06244433 · tracked via the Priya Life Science France tracker
Condition(s) studied
Sudden Infant DeathSudden Unexplained Infant Death
Investigational drug(s) / intervention(s)
whole genome sequencing
whole genome sequencing: Study of all coding and non-coding sequences in the genome to identify pathogenic allelic variants
Study summary
This is a multicenter genetic study aimed at identifying new genes/variants associated with sudden infant death syndrome (SIDS) based on whole-genome sequencing of family trios
Eligibility
Child Inclusion Criteria
* Death of a child between 0 and 2 years of age due to sudden unexpected death in infant
* Child included in the French SUDI registry with effective participation in the biocollection
* Children who also meet the inclusion criteria for the BIOMINRISK-NEUROBIO (axis 2) and BIOMINRISK-RADIO-ANAT (axis 3) studies in the overall BIOMINRISK project.
Parents Inclusion Criteria
* Biological parents of the child included in the BIOMINRISK study
* Parents who have both signed the consent form for blood collection and inclusion of their samples in the biocollection
* parents beneficiaries of a social security or similar scheme
Child Exclusion Criteria:
* Presence of a known metabolic, genetic or syndromic pathology at the time of death
Parents Exclusion Crtiteria:
* Parent under guardianship
* Presence of a known metabolic, genetic or syndromic pathology
Primary outcome measure(s)
- Identification of genetic variants — up to 38 months
Presence of de novo genetic point mutations in coding and non-coding sequences, based on analysis of family trios using a whole-genome sequencing approach
Trial sites (18)
| Facility | City | Region | Status |
|---|---|---|---|
| Nantes University Hospital | Nantes | Loire-Atlantique | Recruiting |
| CHU Amiens | Amiens | France | Recruiting |
| CHU Angers | Angers | France | Recruiting |
| CHU Besançon | Besançon | France | Recruiting |
| APHP - Hôpital Jean Verdier | Bondy | France | Recruiting |
| CHU Brest | Brest | France | Recruiting |
| CHU de Caen-Normandie | Caen | France | Not Yet Recruiting |
| APHP - Hôpital Antoine Béclère | Clamart | France | Recruiting |
| Centre Hospitalier Sud Francilien | Corbeil-Essonnes | France | Not Yet Recruiting |
| CHU Grenoble | Grenoble | France | Recruiting |
| HCL | Lyon | France | Recruiting |
| AP-HM | Marseille | France | Not Yet Recruiting |
| CHU Montpellier | Montpellier | France | Recruiting |
| CHRU Nancy | Nancy | France | Recruiting |
| CHU de Poitiers | Poitiers | France | Not Yet Recruiting |
| CHU Rouen | Rouen | France | Recruiting |
| CHU Saint Etienne | Saint-Etienne | France | Recruiting |
| CHU Toulouse | Toulouse | France | Recruiting |
More Nantes University Hospital trials in France
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06244433 on ClinicalTrials.gov ↗ ← All trials in France