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Recruiting Not applicable

Interest of Intensive Postoperative Rehabilitation Following Minimally Invasive Lung Resection

NCT06202222 · tracked via the Priya Life Science France tracker
Phase
Not applicable
Started
2024-09-09
Last updated
2025-09-10

Condition(s) studied

Lung Cancer

Investigational drug(s) / intervention(s)

rehabilitation

rehabilitation: The patient undergoes a daily session on the cycloergometer (Am3i Ergometer). The patient is instructed to pedal at a heart rate ranging from 60% to 80% of their maximum heart rate (calculated as 220 minus their age) for a duration of 20 minutes. These sessions can be conducted with oxygen therapy for patients dependent on oxygen. The sessions are maintained until the patient is discharged from the department.

Study summary

For patients diagnosed with non-small cell lung cancer (NSCLC), lung resection surgery remains the gold standard for curative treatment. This scheduled operation is associated with significant morbidity, particularly in individuals with impaired cardio-respiratory function. Therefore, patient optimization is paramount. The process begins prior to surgery with preoperative rehabilitation, commonly referred to as "prehabilitation," serving as the foundation for various Enhanced Recovery After Surgery programs. The training methods employed in these programs bear similarity to rehabilitation programs designed for patients with chronic obstructive pulmonary disease (COPD).

Postoperatively, patients undergoing thoracic surgery partake in daily physiotherapy sessions, aiming to optimize the postoperative period, minimize the respiratory impact of surgery, and reduce the length of hospital stay. However, this treatment is not currently standardized and primarily involves early mobilization, including walking, and respiratory physiotherapy. Our focus is on the intensity and methods of this postoperative rehabilitation.

There is limited literature on effective early rehabilitation in the immediate postoperative period, and existing studies suggest no adverse events associated with postoperative training. Therefore, our objective is to assess whether combining endurance training with standard physiotherapy (walking and respiratory physiotherapy) enhances the functional capacity of individuals undergoing lung surgery.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients requiring surgery for diagnosed or undergoing diagnosis of lung cancer. * Patients in need of major lung resection through a minimally invasive approach. * Patients capable of performing the chair rise test. Exclusion Criteria: \- Contraindications to cyclo-ergometry: Deep vein thrombosis in a lower limb. Patients with one or both lower limbs amputated. Rheumatological pathology, trauma, or previous surgery in the lower limb, pelvis, or spine, resulting in limited joint amplitude or strict immobilization. Dermatological conditions with severe lesions preventing prolonged sitting on a bicycle. * Glasgow score less than 15. * Patients who have not undergone pulmonary resection by minimally invasive surgery. * Patients hospitalized outside the thoracic surgery department before the first post-operative visit with the physiotherapist on Day 0.

Primary outcome measure(s)

  • Number of chair lifts at the scheduled visit 30 days after surgery — 30 days after surgery
    number of chair lifts

Trial sites (3)

FacilityCityRegionStatus
Valenciennes, Hospital Valenciennes Hauts-de-France Recruiting
CAEN, university Hospital Caen Normandy Recruiting
Rouen, University Hospital Rouen Normandy Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06202222 on ClinicalTrials.gov ↗ ← All trials in France