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Recruiting Observational

National Registry of Cardioneuroablation in Recurrent Reflex Syncope

NCT06159764 · tracked via the Priya Life Science France tracker
Phase
Observational
Started
2024-11-27
Last updated
2025-06-17

Condition(s) studied

Syncope, VasovagalBradycardiaHeart Arrest

Investigational drug(s) / intervention(s)

Cardioneuroablation

Cardioneuroablation: radiofrequency ablation to destroy cardiac ganglionated plexi located in epicardial fat pads around the atrias

Study summary

This registry aims to collect patient data on cardioneuroablation for vasovagal syncope from multiple centers in France. The aim is to evaluate success rates, compare techniques and help institutions set up their own cardioneuroablation program

Eligibility

Sex
ALL
Min age
18 Years
Max age
100 Years
Healthy volunteers
No
Inclusion Criteria: * Patients aged 18 or more * Recurrent vasovagal syncope (≥2 episodes during the last year) with an asystolic component (≥3 second pause) recorded during a spontaneous episode. The asystole can be related to sinus arrest or paroxysmal AV block. * Scheduled cardioneuroablation procedure * Estimated residual battery life ≥ 1 year. * Patient affiliated to or beneficiary of national health security scheme. * Patient who have received an information notice and has not objected to the use of their data in the registry. Exclusion Criteria: * Contraindication to anticoagulation therapy: major bleeding, risk of major bleeding, severe hepatic disease * Contraindication to cardiac CT: contrast medium allergies * Intracardiac thrombus * Patient detained by judicial or administrative decision.

Primary outcome measure(s)

  • Recurrence of vasovagal syncope — 12 months
    Number of patients with recurrence

Trial sites (14)

FacilityCityRegionStatus
Hôpital Louis Pradel Bron France Recruiting
CHU Clermont-Ferrand Clermont-Ferrand France Recruiting
CHU Lille Lille France Not Yet Recruiting
Hôpital de la Timone Marseille France Recruiting
CHU de Montpellier Montpellier France Not Yet Recruiting
Clinique du Millénaire Montpellier France Recruiting
Hôpital Pitié-Salpêtriére Paris France Recruiting
Hôpital européen Georges Pompidou Paris France Recruiting
Hôpital Haut-Lévèque Pessac France Recruiting
CHR Pontchaillou Rennes France Recruiting
Centre cardiologique du Nord Saint-Denis France Recruiting
Institut ARNAULT TZANCK Saint-Laurent-du-Var France Not Yet Recruiting
Clinique Pasteur Toulouse France Recruiting
CHU de Toulouse Toulouse France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06159764 on ClinicalTrials.gov ↗ ← All trials in France