Neuromodulation in Patients With Neuropathic Pain and Depression.
Condition(s) studied
Investigational drug(s) / intervention(s)
Repetitive transcranial magnetic stimulation (rTMS) - M1/DLPFC: Repetitive transcranial magnetic stimulation (rTMS) is a treatment technique involving the induction of an electrical current on the surface of the cortex by applying a magnetic field to the scalp. This field is generated using a stimulation loop controlled by a robotic arm linked to a neuronavigation system. rTMS of M1 then rTMS of DLPFC.
Repetitive transcranial magnetic stimulation (rTMS) - DLPFC/M1: Repetitive transcranial magnetic stimulation (rTMS) is a treatment technique involving the induction of an electrical current on the surface of the cortex by applying a magnetic field to the scalp. This field is generated using a stimulation loop controlled by a robotic arm linked to a neuronavigation system. rTMS of DLPFC then rTMS of M1.
Study summary
High-frequency repetitive transcranial magnetic stimulation of the primary motor cortex has shown its effect on refractory neuropathic pain, and rTMS of the dorsolateral prefrontal cortex is commonly used for treatment-resistant depression.
The treatment for patients suffering from neuropathic pain and depression, concomitantly, still needs to be studied, as there are some specificities in both symptoms and brain functional MRI.
Eligibility
Primary outcome measure(s)
- Comparison of pain relief rates between the two stimulation targets (M1 and DLPFC) — 2 weeks after the last rTMS session for each arm
Patients are asked how much pain relief they have experienced since the last session.
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| CHU de Saint-Etienne | Saint-Etienne | France | Recruiting |
More Centre Hospitalier Universitaire de Saint Etienne trials in France
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06129890 on ClinicalTrials.gov ↗ ← All trials in France