Ireland
--:--IST
Recruiting Not applicable

Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia

NCT05915663 · tracked via the Priya Life Science France tracker
Phase
Not applicable
Started
2024-11-07
Last updated
2026-09-10

Condition(s) studied

Intubated Patient Requiring a Gastric Tube

Investigational drug(s) / intervention(s)

nasogastric tube and orogastric tubeorogastric tube and nasogastric tube

nasogastric tube and orogastric tube: nasogastric tube in period 1 and orogastric tube in period 2

orogastric tube and nasogastric tube: orogastric tube in period 1 and nasogastric tube in period 2

Study summary

In intensive care, many gastric tubes are inserted on a regular basis. There are different practices in terms of the location of the gastric tube. In some cases, the tube is inserted through the nose and in others, it is inserted through the mouth.

In the literature and in practice, these gastric tubes create discomfort and complications that have an impact not only on the patient, but also on the treatments and the length of the patient's stay in hospital.

Nosocomial Ventilator Associated Pneumonia is the most serious common complication for patients intubated with a gastric tube. It is possible that placement site may have an impact on the risk of developing Ventilator Associated Pneumonia, particularly by increasing the risk of bacterial pullulation opposite the sinuses when the tube is placed via the nasal route.

Investigator hypothesises that placing the gastric tube orally will reduce the rate of ventilator-associated pneumonia compared with the nasal route in mechanically ventilated intensive care patients.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * patient in intensive care, intubated, ventilated * Adult * Requiring a gastric tube * With an expected duration of mechanical ventilation of more than 48 hours * Affiliated to social security * Patient or relative consent or, failing that, emergency inclusion of the patient Exclusion Criteria: * Pregnant, breast-feeding or parturient women * Patients under legal protection: curatorship and guardianship * Contraindication to placing a gastric tube through the nose or mouth * Patients who already have a gastric tube when they enter the service * Patient intubated for more than 24 hours * Patient intubated via the nasotracheal route

Primary outcome measure(s)

  • Compare impact of insertion site of gastric tube on the incidence of ventilator associated pneumoniae — Day 28
    The impact is measured by the number of ventilator associated peumonia

Trial sites (16)

FacilityCityRegionStatus
CHU Angers Angers France Recruiting
CH Cholet Cholet France Recruiting
CHU Grenoble Grenoble France Recruiting
CHD Vendée La Roche-sur-Yon France Recruiting
Centre Hospitalier Du Mans Le Mans France Recruiting
APHM - Hôpital Nord Marseille France Recruiting
CHU Nantes Nantes France Recruiting
CHRU Orléans Orléans France Recruiting
APHP - Hôpital Saint-Antoine Paris France Recruiting
CH Périgueux Périgueux France Recruiting
CHU Poitiers Poitiers France Recruiting
CHU Rennes Rennes France Recruiting
CH Saint-Nazaire Saint-Nazaire France Recruiting
CHRU Strasbourg - Hôpital de Hautepierre Strasbourg France Recruiting
CHIC Toulon - La Seyne sur Mer Toulon France Recruiting
CHRU Tours - Hôpital Bretonneau Tours France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05915663 on ClinicalTrials.gov ↗ ← All trials in France