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Recruiting Observational

A Machine Learning Approach to Identify Patients With Resected Non-small-cell Lung Cancer With High Risk of Relapse

NCT05732974 · tracked via the Priya Life Science France tracker
Phase
Observational
Started
2023-03-30
Last updated
2023-09-21

Condition(s) studied

Non-small Cell Lung Cancer Stage IIIA

Investigational drug(s) / intervention(s)

Resected non small cell lung cancer

Resected non small cell lung cancer: plasma sample, tissue sample and computed tomography scan images

Study summary

Early-stage non small cell lung cancer represents 20-30% of all non small cell lung cancer and is characterized by a high survival probability after surgical resection. However, considering stage IA-IIIA non small cell lung cancer, a relapse rate of about 50% is observed, with a different survival probability on the basis of tumor node metastasis status, although patients within the same tumor node metastasis stage exhibit wide variations in recurrence rate. There are currently no validated prognostic biomarkers able to identify patients with a high risk of relapse.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patient with an early stage of non small cell lung cancer * Indication of surgical resection * Patient able to understand and give his consent * Patient affiliated to the health insurance Exclusion Criteria: * Patient with another cancer in the last 5 years * Patient with an allergy to the contrast medium * Patient under legal protection

Primary outcome measure(s)

  • Algorithm for disease free survival — 18 months
    Analysis on a training cohort of resected early-stage non small cell lung cancer

Trial sites (1)

FacilityCityRegionStatus
Julien MAZIERES Toulouse France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05732974 on ClinicalTrials.gov ↗ ← All trials in France