Ireland
--:--IST
Recruiting Phase 2

Improvement of Lung and Thoracic Compliance in ARDS Patients in Prone Position by Using Inflatable Air Bag

NCT05515484 · tracked via the Priya Life Science France tracker
Phase
Phase 2
Started
2022-08-23
Last updated
2025-05-28

Condition(s) studied

ARDSProne PositionMechanical VentilationAirbag

Investigational drug(s) / intervention(s)

prone position with airbagsprone position without airbags

prone position with airbags: prone position with airbags

prone position without airbags: prone position without airbags

Study summary

ARDS is frequent in ICU and may lead to many complications and to death. Prone position is widely used in ADRS patients and demonstrated to decrease mortality. Regarding the chest wall compliance data are missing but the theorical response is that this compliance is decreased in a prone position mainly due to anterior chest and abdomen compression in this position which are more compliant that dorsal part of the body. As well prone position could be associated with complications as pressure ulcers. Because prone position is associated with complications, air bag were developped to decrease pressure on the chest and abdomen and to decrease pressure ulcers. Then, trying to improve chest compliance in prone position and reducing the risk of pressures ulcers could be a challenge with this system in comparison with standard care.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * patients with ARDS under mechanical ventilation with P/F ratio\<150 * Age \>18 y/o * Admitted in the medical ICU of Amiens under mechanical ventilation sedated, * With signed informed consent (patient or relative if patient is not conscious) Exclusion Criteria: * patients not eligible for a prone position * Patients with tracheostomy

Primary outcome measure(s)

  • variation of Lung compliance between both groups — 3 days

Trial sites (1)

FacilityCityRegionStatus
CHU Amiens Amiens France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05515484 on ClinicalTrials.gov ↗ ← All trials in France