Language Acquisition in the Brain and Algorithms: Towards Systematic Monitoring of the Evolution of Semantic Representations in Biological and Artificial Neural Networks

Condition(s) studied

Investigational drug(s) / intervention(s)

intracranial brain recording: Any patient benefiting from a long-term intracranial brain recording.

Study summary

Speech depends on our ability to recursively combine successive words into a complex sense. Although the order of these putative operations (syntax) has been the subject of extensive examination in the way in which the human brain learns to perform a "Semantic composition" remains largely unknown.

The Rothschild Hospital houses a unit specializing in drug-resistant epilepsy in children from 2 to 20 years old.

The identification of the epileptogenic zone often requires making an iEEG recording for a week (implantation of intracerebral electrodes in depth).

Sometimes this recording has to be repeated, providing a unique opportunity to directly record brain activity at different periods of its development.

Children will listen to pre-recorded phrases and stories such as "The Little Prince of Antoine de Saint-Exupéry" while being recorded with iEEG.

Eligibility

Primary outcome measure(s)

• This is a non-clinical research study investigating from intracranial recordings how speech representation changes throughout human development. — maximum 21 days
  intracranial recordings

Trial sites (1)

More Fondation Ophtalmologique Adolphe de Rothschild trials in France