Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis Collection

Condition(s) studied

Investigational drug(s) / intervention(s)

Collection of biological sample with sera, CSF, buffy coat, PBMC, plasma.: Blood is collected only one time by blood sample to obtain serum, buffy coat, plasma and PBMC. 2 \*4ml of blood on dry tube 2 \*4ml of blood on EDTA tube If possibility of delivery in 48 hours at the Centre of Biological Resources, 7\*4ml of blood on heparin tube If cerebrospinal fluid has been drawn for diagnosis, remaining sample available will be stored in the collection

Study summary

Numerous neurological disorders affecting the central and peripheral nervous system can be attributed to the immune system through multiple effector mechanisms. However, current treatments could be drastically improved by faster and more accurate diagnosis. The sample collection will benefit to patients with rare neuroimmune syndromes such as Autoimmune Encephalitis (AE) and Paraneoplastic Neurological Syndromes (PNS) leading to a better and early diagnosis, as well as treatment improvement.

Eligibility

Primary outcome measure(s)

• Blood Samples — 10 years
  Assessment of biocollection of blood samples
• Cerebrospinal fluid biocollection — 10 years
  Assessment of biocollection of Cerebrospinal fluid

Trial sites (62)

+ 22 more sites — see the full list on the official registry below.

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