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Clinical Trials in France / NCT05089747
Recruiting Observational

CIRculating CANcer MAster-Protocol

NCT05089747 · tracked via the Priya Life Science France tracker
Sponsor
Hospices Civils de Lyon
Phase
Observational
Started
2022-12-05
Last updated
2026-06-10

Condition(s) studied

Adult With Solid Cancer

Investigational drug(s) / intervention(s)

Blood sampling for biomarker analysis (microRNA, circulating DNA…)

Blood sampling for biomarker analysis (microRNA, circulating DNA…): From one to four blood samplings: at diagnosis, after the first cycle of treatment, end of treatment, progressive disease (or end of study).

Study summary

This exploratory study will focus on the development of the analyses of blood biomarkers to better understand the circulating biomarkers associated with cancer diagnosis, treatment efficacy and progressive disease

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Adult (\>18y) * Owing a social security insurance * Any solid cancer diagnosed by histopathology or cytology * Patient with blood sampling required as per standard of care * Informed consent signed Exclusion Criteria: * Refusal to participate * No blood sampling required as per standard of care * Hemoglobin \< 7g/dl (\< 9g/dl if respiratory or cardiovascular disease history) * Heterologous blood transfusion in the last 48 hours * Weight under 20 kg

Primary outcome measure(s)

  • Liquid biopsy analyses — Day 0
    Extraction of circulating DNA or circulating RNA followed by a tumoral cells extraction.
  • Standard technics of disease assessment — Week 16
    Genetic and transcriptomic explorations with immunofluorescence technique. Marking with specific markers of the tumor pathology. And enumaration of tumoral cells.
  • Correlation between outcome 1 and outcome 2 — year 5
    Building a biological collection of blood samples and following, diagnosis and prediction of adult solid cancer.

Trial sites (7)

FacilityCityRegionStatus
Service de Pneumologie Hôpital Louis Pradel / Groupement Hospitalier Est Bron France Recruiting
Hôpital Edouard Herriot / Groupement Hospitalier Centre Lyon France Recruiting
Service de Pneumologie Hôpital Croix-Rousse / Groupement Hospitalier Nord Lyon France Recruiting
Service de Pneumologie Aigue Spécialisée et Cancérologie Thoracique Hôpital Lyon-Sud / Groupement Hospitalier Sud Pierre-Bénite France Recruiting
Hôpital Lyon-Sud / Groupement Hospitalier Sud Pierre-Bénite France Recruiting
Oncologie médicale Hôpital Lyon-Sud / Groupement Hospitalier Sud Pierre-Bénite France Recruiting
Service de dermatologie Hôpital Lyon-Sud / Groupement Hospitalier Sud Pierre-Bénite France Recruiting

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Validation of the French Version of the New Mobility Score (NMS) Recruiting
Burosumab and 1-25 (OH) Vitamin D on Human Osteoblasts Recruiting
Impact of Mental Health First Aid-trained Peers on the Mental Well-being of First-year Medical Residents. Active, not recruiting
Psychological Support Interventions for Women With Endometriosis (ENDOPSY) Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05089747 on ClinicalTrials.gov ↗ ← All trials in France