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Clinical Trials in France / NCT04690972
Recruiting Observational

"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

NCT04690972 · tracked via the Priya Life Science France tracker
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Phase
Observational
Started
2021-01-14
Last updated
2026-02-12

Condition(s) studied

Chronic Liver Disease and CirrhosisLiver CancerNon-Alcoholic Fatty Liver DiseaseNon-Alcoholic SteatohepatitisViral Hepatitis BViral Hepatitis CViral Hepatitis D

Investigational drug(s) / intervention(s)

Blood sample during surgeryTaking an additional biopsyBlood sample during diagnostic test

Blood sample during surgery: During the hepato-bilio-pancreatic surgery, blood is drawn.

Taking an additional biopsy: As part of the treatment, an additional biopsy is executed and blood is drawn.

Blood sample during diagnostic test: Blood sample as part of the care

Study summary

Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: 1. Patients * diagnosed with chronic liver disease (viral or not) * diagnosed with at least one liver nodule for which a biopsy is planned as part of the care * for hepatobiliary surgery planned as part of care * for locoregional treatment for HCC is indicated 2. Patients able to receive and understand information relating to the study and give their written informed consent 3. Patients affiliated to the French social security system Exclusion Criteria: 1. Minor patients 2. Patients under legal protection, 3. Patients subject to legal protection or unable to express their consent, 4. Patients in a situation of social fragility, 5. Pregnant or breastfeeding woman, 6. No signing of informed consent.

Primary outcome measure(s)

  • Surgery for a hepato-bilio-pancreatic issue — through study completion, an average of 8 year
    Patients whom hepato-bilio-pancreatic disease

Trial sites (1)

FacilityCityRegionStatus
PU-PH, Directeur de l'UMR_S1110 Unité Inserm d'affiliation : UMR_S1110 Strasbourg France Recruiting

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Other trials for the same condition

CHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome Recruiting
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Oncology, Undernutrition and Sensoriality: Links, Mechanisms and Levers for Action Recruiting
Phase 2b Study of GSK4532990 in Adults With NASH Active, not recruiting
FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer. Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04690972 on ClinicalTrials.gov ↗ ← All trials in France