VIsual Cerebral ConnecTivity On Functional Magnetic Resonance Imaging in Patients With Hereditary REtinal Dystrophies

Condition(s) studied

Investigational drug(s) / intervention(s)

IRMf-r (séquence resting state): Functional MRI of functional brain networks

Study summary

The Rothschild Foundation A Hospital follows a cohort of approximately 300 patients with hereditary retinal dystrophy. These patients are followed in ophthalmology consultation every year. In order to plan the MRI on the day of the annual consultation and to avoid additional travel for patients, patients will be informed of the study before the consultation (transmission of an information letter and the information note from study). If patients agree to participate in the study, rMRI will be scheduled. During the follow-up ophthalmologic consultation, after checking the inclusion and non-inclusion criteria, the study information will be repeated, and patients who still agree to participate will sign the study consent.

Eligibility

Primary outcome measure(s)

• Localization and characterization of neural networks — baseline
  neuronal networks description using rest and morphological functionnal MRIs
• Evolution of neuronal networks after retinal implantation — baseline
  neuronal networks description using rest and morphological functionnal MRIs

Trial sites (1)

More Fondation Ophtalmologique Adolphe de Rothschild trials in France