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Clinical Trials in France / NCT03905239
Recruiting Not applicable

A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction

NCT03905239 · tracked via the Priya Life Science France tracker
Sponsor
Centre Hospitalier Universitaire, Amiens
Phase
Not applicable
Started
2019-04-01
Last updated
2025-06-08

Condition(s) studied

Small Bowel Obstruction

Investigational drug(s) / intervention(s)

algorithm

algorithm: clinical examination and procalcitonin assessment

Study summary

Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically. However, the choice between these two approaches can be difficult due to the absence of specific signs. The objective of this study is to evaluate the clinical impact of a procalcitonin-based algorithm.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Uncomplicated acute adhesion-related small bowel obstruction (ASBO) * Adults * Patients able to express consent * Signed written informed consent form * Covered by national health insurance Exclusion Criteria: * Disease-related criteria: * Large bowel obstruction * No previous abdominal surgery * Signs of peritonitis or strangulation requiring emergency surgery) * Obstruction within 4 weeks following previous surgery * Ongoing or history of bowel cancer * Ongoing or in history of inflammatory bowel disease * History of abdominal radiotherapy * Active infection * Contraindication to contrast-enhanced CT scan * Minors * Patient deprived of liberty by administrative or judicial decision or placed under judicial protection (guardianship or supervision) * Pregnancy or breastfeeding

Primary outcome measure(s)

  • proportion of patients achieving textbook outcome — within 90 days after randomization.
    textbook outcome is defined as patients either correctly operated (ischemia confirmed at operation ± resection) or correctly managed conservatively (no need for unplanned surgery) with no major postoperative complications (Clavien-Dindo≥3) and a medical length of stay\<5 days (defined as the time at which the patient is medically eligible for discharge), with no postoperative consultation, rehospitalisation and reoperation within 90 days after randomization.

Trial sites (1)

FacilityCityRegionStatus
Amiens Universitary Hospital Amiens France Recruiting

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Other trials for the same condition

Contribution of Point of Care Ultrasound by the Emergency Physician to Rule Out the Small Bowel Obstruction: a Diagnostic, Multicenter Study Recruiting
Early Surgery Versus 3 Days Non-surgical Management in Acute Small Bowel Obstruction (SURGI-BOW) Recruiting
Predicting NOM Failure in Bowel Obstruction Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03905239 on ClinicalTrials.gov ↗ ← All trials in France