Clinical Trials in France / NCT03065686
Recruiting
Not applicable
Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing
NCT03065686 · tracked via the Priya Life Science France tracker
Condition(s) studied
Cleft Lip and Palate
Investigational drug(s) / intervention(s)
identification of genetic factors
identification of genetic factors: Clinical questionnaire and analysis of genetic data obtained by exome high-throughput sequencing
Study summary
Despite significant progress made in identification on numerous genes and gene pathways critical for craniofacial development, several approaches, ie mutation screening of specific candidates, association studies and even genome-wide scans have largely failed to reveal the molecular basis of NS human clefting
Eligibility
Inclusion Criteria:
* Subject with a NSCL/P or CL/P of unknown etiology,
* national health care insurance holders
Exclusion Criteria:
* Subject with a CL/P of known etiology,
* Subject with a NSCL/P and an IRF6 mutation
Primary outcome measure(s)
- Identification of genetic factors — Day 1
Identification of genetic factors implicated in orofacial cleft using whole exome sequencing (WES).
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| CHU Amiens Picardie | Amiens | France | Recruiting |
More Centre Hospitalier Universitaire, Amiens trials in France
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT03065686 on ClinicalTrials.gov ↗ ← All trials in France