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Clinical Trials in the EU / 2025-522170-36-00
Authorised, recruitment ended Phase III

I4V-MC-JAJK: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Baricitinib to Preserve Beta Cell Function in Participants Newly Diagnosed With Type 1 Diabetes Aged ≥1 to <36 Years

2025-522170-36-00 · tracked via the Priya Life Science EU tracker
Sponsor type
Pharmaceutical company
Therapeutic area
Nutritional and Metabolic Diseases
Decision date
03/02/2026
Enrollment target
183
Sites
Finland, Germany, Italy, France, Sweden, Poland, Spain, Belgium, Czechia, Netherlands, Portugal, Norway

Condition studied

Diabetes Mellitus, Type 1

Investigational medicinal product(s)

BaricitinibBARICITINIBPlacebo to match LY

Eligibility

Age group
18-64 years, 0-17 years
Sex
Female, Male

Primary endpoint

Change from Baseline in C-peptide Area Under the Curve (AUC) [Time Frame: Baseline, Week 52]

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-522170-36-00 on CTIS ↗ ← All trials in the EU