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Clinical Trials in Egypt / NCT07884006
Starting soon Observational

Impact of Nutritional Status Before Joint Replacement on Infection Risk

NCT07884006 · tracked via the Priya Life Science Egypt tracker
Sponsor
Assiut University
Phase
Observational
Started
2026-12-01
Last updated
2026-10-20

Condition(s) studied

Periprosthetic Joint Infection (PJI)MalnutitrionPostoperative Complication

Study summary

Periprosthetic joint infection (PJI) is a serious complication after joint replacement surgery and is difficult to treat. Poor nutritional status may impair the body's ability to recover and fight infection, as well as increase the risk of postoperative problems. The CONUT (Controlling Nutritional Status) score is a nutritional assessment tool that is based on 3 standard blood parameters, serum albumin, total cholesterol and total lymphocyte count. This study is a prospective observational study to investigate the association of preoperative nutritional status as defined by CONUT score and the risk of periprosthetic joint infection in patients undergoing joint arthroplasty. Preoperative nutritional assessment and postoperative follow-up will be performed to detect the occurrence of periprosthetic joint infection. We are studying whether a higher preoperative CONUT score is associated with a higher risk of infection after joint replacement surgery. The findings may help to identify those who are at increased risk of surgical infection and promote better preoperative assessment and patient care."

Eligibility

Sex
ALL
Min age
40 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients aged 40 years or older who undergo primary joint arthroplasty, including knee arthroplasty and hip arthroplasty, who have complete preoperative laboratory data required for calculation of the CONUT score and provide written informed consent will be included. Exclusion Criteria: * Patients who had undergone revision surgery, suffered from active infections, had malignancies, or had incomplete follow-up will not be included in our study.

Primary outcome measure(s)

  • Incidence of periprosthetic joint infection — Up to 6 months
    The rate of patients who develop periprosthetic joint infection (PJI) after primary joint arthroplasty. PJI will be diagnosed based on the established diagnostic criteria. The incidence of PJI will be evaluated in relation to preoperative nutritional status assessed by the Controlling Nutritional Status (CONUT) score.

Trial sites (1)

FacilityCityRegionStatus
Assiut University Asyut Asyut Governorate

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07884006 on ClinicalTrials.gov ↗ ← All trials in Egypt