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Clinical Trials in Egypt / NCT07882095
Starting soon Not applicable

Immediate vs Conventional Loading With Different Crown Materials on Immediately Placed Single Implants

NCT07882095 · tracked via the Priya Life Science Egypt tracker
Sponsor
Ain Shams University
Phase
Not applicable
Started
2026-11-25
Last updated
2026-10-20

Condition(s) studied

Partial EdentulismDental ImplantTooth Loss in the Esthetic Zone Requiring Immediate Implant Placement

Investigational drug(s) / intervention(s)

Conventional loadingMonolithic zirconia crownPermanent 3D-printed PMMA crownTemporary 3D-printed PMMA crown

Conventional loading: Cover screw and 3 months of unloaded healing, then a screw-retained crown in full occlusion.

Monolithic zirconia crown: CAD-CAM milled monolithic zirconia (Zolid fx, Amann Girrbach) screw-retained crown on a Ti-base.

Permanent 3D-printed PMMA crown: DLP-printed (AccuFab D1s) permanent PMMA-based resin crown on a Ti-base.

Temporary 3D-printed PMMA crown: DLP-printed (AccuFab D1s) provisional PMMA-based resin crown on a Ti-base.

Study summary

This randomized controlled trial compares immediate and conventional loading of single implants placed immediately into fresh extraction sockets in the upper front and premolar region. Eighty adults will be randomly assigned to four groups: immediate loading (within 48 hours) with a definitive zirconia crown, a permanent printed PMMA crown, or a temporary printed PMMA crown, or conventional loading with a definitive zirconia crown after 3 months. All implants are placed with a fully guided digital workflow.

Eligibility

Sex
ALL
Min age
21 Years
Max age
50 Years
Healthy volunteers
No
Inclusion Criteria: * Age 21 years or older * Single tooth requiring extraction and replacement in the maxillary anterior or premolar region (sites 15 to 25), with a gap bounded by natural teeth * Adjacent tooth present * Opposing dentition of natural teeth or a fixed tooth- or implant-supported prosthesis * Extraction socket Elian Type I or Type II * Adequate oral hygiene: bleeding on probing \<20% and plaque index \<20% * Implant insertion torque ≥35 Ncm at placement Exclusion Criteria: * Pregnant or lactating women * Systemic or local contraindication to implant treatment * Smokers * Current drugs affecting bone metabolism * Bisphosphonate use in the last 4 years * Malignancy, radiotherapy or chemotherapy for malignancy in the past 5 years

Primary outcome measure(s)

  • Peri-implant marginal bone level change — Baseline (implant placement) to 12 months; also measured at 6 months
    Change in distance (mm) from implant platform to first bone-implant contact

Trial sites (2)

FacilityCityRegionStatus
Assiut University Asyut Asyut Governorate
Ain Shams University Cairo Cairo Governorate

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Other trials for the same condition

Carrot Technique Versus Guided Bone Regeneration for Horizontal Ridge Deficiency in the Maxillary Esthetic Zone Active, not recruiting
Evaluation of Guided Tissue Regeneration With Autogenous Bone Chips and CGF During Implant Placement Starting soon
Comparing Dynamic Navigation to Static Navigation in the Implant Placement Recruiting
Evaluation of Zygomatic Implant Placement Accuracy Using Fully Metallic vs Resin-based Static Surgical Guides in Severely Atrophic Maxilla Recruiting
Effect of Systemic Vitamin D on Dental Implant Osseointegration Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07882095 on ClinicalTrials.gov ↗ ← All trials in Egypt