Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact
Starting soon Not applicable

Effectiveness of Sensorimotor Proprioceptive Stimulation Combined With Conventional Physical Therapy on Symptoms, Sensory Function, Proprioception, and Hand Function in Patients With Mild-to-Moderate Carpal Tunnel Syndrome

NCT07875751 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2026-10-05
Last updated
2026-10-15

Condition(s) studied

Carpel Tunnel Syndrome

Investigational drug(s) / intervention(s)

sensorimotor proprioceptive stimulationconventional physical therapy

sensorimotor proprioceptive stimulation: Participants will receive sensorimotor proprioceptive stimulation combined with conventional physical therapy. The program will include joint-position training, tactile sensory stimulation, wrist and hand coordination exercises, tendon and median-nerve gliding, grip and pinch activities, and progressive functional hand exercises.

conventional physical therapy: Participants will receive conventional physical therapy alone, including education, ergonomic advice, wrist and hand range-of-motion exercises, tendon-gliding exercises, strengthening exercises, and a standardized home-exercise program.

Study summary

This randomized controlled trial will evaluate whether adding sensorimotor proprioceptive stimulation to conventional physiotherapy improves symptoms and hand function in patients with mild-to-moderate carpal tunnel syndrome. The primary outcome is change in the Boston Symptom Severity Scale, while secondary outcomes include functional status, pain, paresthesia, nerve conduction, median-nerve morphology, proprioception, and hand strength.

Eligibility

Sex
ALL
Min age
30 Years
Max age
50 Years
Healthy volunteers
No
Inclusion Criteria: * Are adults aged 30-50 years. * Have clinically diagnosed mild-to-moderate carpal tunnel syndrome. * Report pain, numbness, tingling, or nocturnal symptoms in the median-nerve distribution. * Have symptoms lasting at least 4 weeks. * Have electrodiagnostic findings consistent with mild-to-moderate median-nerve compression at the wrist. * Can understand and follow study instructions. * Can attend treatment and assessment sessions. * Provide written informed consent. Exclusion Criteria: * Severe carpal tunnel syndrome requiring immediate surgery. * Previous carpal tunnel release or wrist surgery. Cervical radiculopathy, brachial plexopathy, or another peripheral neuropathy. * Diabetes, rheumatoid arthritis, thyroid disease, or other systemic conditions affecting nerve function, unless medically stable and permitted by the protocol. * Wrist fracture, arthritis, tendon injury, or other upper-limb musculoskeletal disorders. * Pregnancy.

Primary outcome measure(s)

  • Boston Carpal Tunnel Questionnaire Symptom Severity Scale — baseline
    The Boston Carpal Tunnel Questionnaire Symptom Severity Scale consists of 11 items assessing pain, numbness, tingling, weakness, nocturnal symptoms, and difficulty grasping objects. Each item is scored from 1 to 5. The total score will be calculated as the mean of the 11 item scores: Mean SSS score = sum of the 11 item scores ÷ 11 The final score ranges from 1 to 5, with higher scores indicating greater symptom severity.

Trial sites (1)

FacilityCityRegionStatus
Nile Physio Clinic Al Mansurah Egypt
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07875751 on ClinicalTrials.gov ↗ ← All trials in Egypt