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Active, not recruiting Not applicable

Comparative Study Between the Effects of Deep Versus Moderate Neuromuscular Blockade on Postoperative Recovery and Immune Function in Patients Undergoing Total Hip Replacement Surgery.

NCT07870954 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2026-06-20
Last updated
2026-10-13

Condition(s) studied

Immune ResponsesPost Operative Recovery

Investigational drug(s) / intervention(s)

ToF ( Train of Four) Scan

ToF ( Train of Four) Scan: Depth of NMB will be monitored continuously using the ToFScan. The target NMB depth will be maintained until skin closure

Study summary

. The investigators hypothesized that DNMB ( Deep NeuroMuscular Block) would yield superior postoperative recovery quality and attenuate the surgery-induced immune suppression compared to MNMB ( Moderate NeuroMuscular Block)in patients undergoing THA (Total Hip Arthroplasty).

Eligibility

Sex
ALL
Min age
16 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * Adult patients (ASA physical status I-III). * Elective, primary THA under general anesthesia Exclusion Criteria: * Neuromuscular disease. * Renal/hepatic impairment. * Allergy to NMBAs or reversal agents. * Pregnancy. * Chronic opioid use.

Primary outcome measure(s)

  • Quality of Recovery-15 (QoR-15) — 24 hours post operative
    questionnaire score at 24 hours postoperatively with higher scores to be better outcomes

Trial sites (1)

FacilityCityRegionStatus
Faculty of Medicine, Sohag University Sohag Egypt
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07870954 on ClinicalTrials.gov ↗ ← All trials in Egypt