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Clinical Trials in Egypt / NCT07855354
Recruiting Not applicable

Safety and Efficacy of Papillary Versus NonPapillary Access During Percutaneous Nephrolithotomy

NCT07855354 · tracked via the Priya Life Science Egypt tracker
Sponsor
Ain Shams University
Phase
Not applicable
Started
2025-11-01
Last updated
2026-10-02

Condition(s) studied

SafetyEfficacyPapillaryNonPapillaryPercutaneous Nephrolithotomy

Investigational drug(s) / intervention(s)

Papillary access punctureNon-papillary access puncture

Papillary access puncture: Patients will undergo papillary access puncture (Control group)

Non-papillary access puncture: Patients will undergo non-papillary access puncture

Study summary

This study aims to evaluate and compare the safety, efficacy, and clinical outcomes of papillary and non-papillary renal access during percutaneous nephrolithotomy (PCNL), and to determine whether non-papillary puncture can be considered a safe and effective alternative to the conventional papillary approach in selected patients.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age ≥ 18 years * Solitary or multiple renal calculi ≥2 cm * Ability to provide informed consent Exclusion Criteria: * Bleeding diathesis or uncorrected coagulopathy * Active urinary tract infection at the time of surgery * Congenital anomalies severely distorting renal anatomy (e.g., horseshoe kidney, ectopic kidney) * Morbid obesity \[body mass index (BMI) ≥ 40\] limiting safe positioning * Pregnancy

Primary outcome measure(s)

  • Stone-free rate — 4 weeks postoperatively
    Stone-free rate will be assessed at 4 weeks postoperatively using non-contrast computed tomography (CT). It will be defined as the absence of residual stones or the presence of clinically insignificant residual fragments (asymptomatic, non-obstructive fragments 2:3mm).

Trial sites (1)

FacilityCityRegionStatus
Ain Shams University Cairo Egypt Recruiting

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Other trials for the same condition

Flexible Nephroscopy-Assisted Single-Tract Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones Recruiting
Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation Starting soon
Tamsulosin Monotherapy Versus Combination Therapy With Tadalafil (2.5 mg vs 5 mg) in Managing Male LUTS Secondary to BPH Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07855354 on ClinicalTrials.gov ↗ ← All trials in Egypt