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Clinical Trials in Egypt / NCT07852026
Starting soon Observational

Role of Total Thyroidectomy in Relieving Local Symptoms in Hashimoto's Thyroiditis

NCT07852026 · tracked via the Priya Life Science Egypt tracker
Sponsor
Assiut University
Phase
Observational
Started
2026-10-01
Last updated
2026-10-01

Condition(s) studied

Hashimoto ThyroiditisGoiter

Investigational drug(s) / intervention(s)

Total Thyroidectomy

Total Thyroidectomy: Surgical removal of the entire thyroid gland performed under general anesthesia for patients with Hashimoto's thyroiditis presenting with compressive or local neck symptoms.

Study summary

This study aims to evaluate the role and effectiveness of total thyroidectomy in relieving compressive and local symptoms (such as dysphagia, dyspnea, and anterior neck pain/discomfort) in patients with Hashimoto's thyroiditis who fail to improve with conservative medical management.

Eligibility

Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: * Adults patients with confirmed Hashimoto's thyroiditis (elevated serum anti-thyroid peroxidase \\anti-thyroglobulin antibodies, characteristic ultrasound findings and/or positive fine needle aspiration cytology) * Biochemically euthyroid with normal thyroid function test. * Presence of persistent local symptoms (neck pain, throat discomfort,neck tightness,chocking) for more than 6 months * Patient fit and motivated to surgery. Exclusion Criteria: * Confirmed or high-suspicion thyroid malignancy (Bethesda V or IV on FNAC * Previous thyroid or neck surgery * Patient refusal to participate in the study * Severe comorbidities precluding general anesthesia * Active psychiatric illness

Primary outcome measure(s)

  • Improvement or Relief of Local Compressive Symptoms — 6 months postoperatively
    Assessment of changes in patient-reported compressive symptoms (such as dysphagia, dyspnea, and local neck discomfort or pressure) following total thyroidectomy compared to baseline status.

Trial sites (1)

FacilityCityRegionStatus
Assiut University Hospitals Asyut Asyut Governorate

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07852026 on ClinicalTrials.gov ↗ ← All trials in Egypt