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Starting soon Not applicable

Wrist Nerve Block as a New Treatment in Patients With Rheumatoid Arthritis

NCT07814989 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2026-08-15
Last updated
2026-09-11

Condition(s) studied

Rhematoid Arthritis

Investigational drug(s) / intervention(s)

Wrist local steroid injection

Wrist local steroid injection: Wrist nerve block by injection is a diagnostic or therapeutic procedure used to treat chronic wrist pain, typically arising from arthritis or instability, by interrupting sensory nerve signals (mainly PIN/AIN nerves) with an anesthetic or neurolytic agent. This less-invasive approach provides pain relief, often serving as a predictor for success before permanent surgical denervation.\[4\]

Study summary

Rheumatoid arthritis is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues.\[1\]

Eligibility

Sex
ALL
Min age
16 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: 1. RA patients fulfilled the 2010 American College of Rheumatoid Arthritis classification criteria.\[8\] 2. Oligoarticular RA patients including wrist joint. 3. Age above 18 years old. 4. Patient cooperative and can answer questions. Exclusion Criteria: 1. Other rheumatologic or collagen diseases. 2. Age below 18 years. 3. Patients who underwent concomitant procedures to address underlying pathology such as radial styloidectomy, ulna shortening, fracture fixation, arthroplasty, arthrodesis, and ligament reconstructions. 4. Patients who suffered from hand deformities or limitation. 5. Uncooperative patients.

Primary outcome measure(s)

  • Change in wrist pain severity measured by the Visual Analogue Scale (VAS) from baseline to Week 16 — Baseline to Week 16
    Change in wrist pain severity measured using the Visual Analogue Scale (VAS) from baseline to Week 16 Visual Analogue Scale (VAS), ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Wrist pain severity will be assessed using the Visual Analogue Scale (VAS), ranging from 0 to 10, where 0 represents no pain and 10 represents the worst imaginable pain. Higher scores indicate greater pain. The change in VAS score from baseline to Week 16 will be assessed.
  • Assessment of wrist pain improvement — 16 weeks
    • Change in wrist pain severity measured by the Visual Analogue Scale (VAS) from baseline to Week 16

Trial sites (1)

FacilityCityRegionStatus
Sohag University Hospital Sohag Egypt
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07814989 on ClinicalTrials.gov ↗ ← All trials in Egypt