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Recruiting Observational

Internal Jugular Vein Collapsibility Index for Volume Status Assessment in Preeclampsia in Correlation With Normotensive Parturients

NCT07786246 · tracked via the Priya Life Science Egypt tracker
Phase
Observational
Started
2025-10-01
Last updated
2026-09-10

Condition(s) studied

Pre-EclampsiaPreeclampsia

Study summary

This study aims to assess and analyze volume status in preeclamptic patients and compare these parameters with those of normotensive pregnant ones based on the change in internal jugular vein ultrasound-based indices.

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
40 Years
Healthy volunteers
Accepted
Inclusion Criteria: 1. Singleton parturients from 18 to 40 years old. 2. Either normotensive or preeclamptic parturients scheduled for elective cesarean section under neuro-axial block matched for gestational age 28-40 weeks will be included: 3. Normotensive group: uncomplicated normotensive pregnancy with systolic blood pressure below 140 mmHg and diastolic blood pressure below 90mmHg without proteinuria. 4. Preeclamptic Group: new onset preeclamptic pregnant female with gestational hypertension after 20 weeks of pregnancy diagnosed based on ISSHP Guidelines: systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥90 mmHg, accompanied by one or more of the following: * Proteinuria (≥300 mg in a 24-hour urine sample) * Alb/Cr ratio ≥30 mg/mmol, * Organ dysfunction (renal insufficiency (creatinine level\>1.1mg%), liver involvement (liver enzyme levels ≥3 times normal), neurological complications (Headache and blurring of vision) and hematological involvement (thrombocytopenia\<100.000)). Exclusion Criteria: 1. Parturients with pre-existing cardiac \& vascular disease affecting blood volume and vascular compliance: (Valvular or congenital heart disease, arrhythmia, previous history of venous thromboembolism, chronic kidney disease, gestational diabetes). 2. multiple gestations 3. known thyroid disorders or chronic hypertension 4. patients with BMI \>40 and patients requiring emergency delivery.

Primary outcome measure(s)

  • Measuring internal jugular vein (IJV) collapsibility index — Intra-operative
    Measuring internal jugular vein (IJV) collapsibility index at end expiratory phase just before the induction of anesthesia and its correlation with normotensive parturients to determine the cut off value of fluid status in preeclamptic patient

Trial sites (1)

FacilityCityRegionStatus
Tanta University Hospital Tanta El-Gharbia Govenorate Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07786246 on ClinicalTrials.gov ↗ ← All trials in Egypt