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Clinical Trials in Egypt / NCT07706348
Recruiting Phase 1/2

Intraperitoneal Irrigation of Ondansteron in Combination With Lidocaine in Acute Postoperative Pain

NCT07706348 · tracked via the Priya Life Science Egypt tracker
Sponsor
Assiut University
Phase
Phase 1/2
Started
2026-06-01
Last updated
2026-07-15

Condition(s) studied

Acue Postoperative Pain

Investigational drug(s) / intervention(s)

ondansteron

ondansteron: intraperitonel irrigation

Study summary

This study, therefore, aimed to investigate the effect of intraperitoneal administration of ondansetron in combination to lidocaine for postoperative pain management in patients undergoing lower abdominal cancer surgery.

Eligibility

Sex
ALL
Min age
20 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: * ASA I-II patients * scheduled for major lower abdominal cancer surgeries. Exclusion Criteria: * patients with known allergy to the study drugs, * significant cardiac, respiratory, renal or hepatic disease, * body mass index (BMI) ≥30 kg/m2; * allergy to study drugs * history of opioid use for pain management the time of enrolment or drug addiction, * who had used benzodiazepine chronically, * stroke or psychiatric disease that could affect the perception of pain.

Primary outcome measure(s)

  • total morphine consumption — in the first 24 hours postoperative
    total amount of morphine consumption in mg in the first 24 hours for analgesia

Trial sites (1)

FacilityCityRegionStatus
Assiut University - South Egypt Cancer Instiute Asyut Egypt Recruiting

More Assiut University trials in Egypt

Combined Hystroscopic and Laparoscopic Repair of CS Scar Disorder Recruiting
The Outcome of Inserting Intercostal Tube or Pleurodesis for Malignant Pleural Effusion Starting soon
Maternal Iron Deficiency and/or Iron Deficiency Anemia to Neonatal Hemoglobin Concentration and Iron Stores Starting soon
Real-Time (TRUS) Guidance in Endoscopic Treatment of BPH Starting soon
Intraoperative Lidocaine Infusion Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07706348 on ClinicalTrials.gov ↗ ← All trials in Egypt