Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact
Starting soon Not applicable

Different Endoscopic Approaches for Sphenoid Sinus

NCT07702188 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2026-08-01
Last updated
2026-07-14

Condition(s) studied

Sphenoid SinusEndoscopic Sinus Surgery

Investigational drug(s) / intervention(s)

endoscopic sinus surgery

endoscopic sinus surgery: Different approaches include: type I, sphenoid ostial dilation. type IIa, transnasal sphenoidotomy (sphenoidotomy without ethmoidectomy). type IIb, transethmoidal sphenoidotomy (sphenoidotomy with ethmoidectomy). type III, bilateral, common cavity sphenoidotomy, or "sphenoid drill-out;" type IV, transpterygoid approach, to expose the lateral sphenoid sinus recess. type V, sphenoid nasalization, completely removing the sphenoid sinus floor.

Study summary

* Identification of the most effective approach for different lesion types
* Correlation between approach and complication rates

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients with sinonasal lesions involving sphenid sinus with or without skull base extension. Exclusion Criteria * Severe comorbidities contraindicating surgery * malignant tumer extend beyond sphenoid sinus requiring open management

Primary outcome measure(s)

  • To evaluate different endoscopic surgical approaches to the sphenoid sinus — 6 months
    * Complete lesion removal measured by post operative imaging ct * Complications examples Csf leakage Optic nerve injury (measured by visual acuity) * Carotid artery injury(bleeding) * Infection(meningitis csf examination if suspected)
  • To evaluate different endoscopic surgical approaches to the sphenoid sinus regarding: * Completence of lesion removal. * Complications. - Csf leakage - Optic nerve injury — 6 month
    complications rate (csf leakage , optic nerve injury, carotid artery injury) * Recurrence * Endoscopic patency of sphenoid osteum and synechia formation

Trial sites (1)

FacilityCityRegionStatus
Assiut University Hospital Asyut Egypt
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07702188 on ClinicalTrials.gov ↗ ← All trials in Egypt