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Clinical Trials in Egypt / NCT07661758
Recruiting Phase 3

Intravenous Lidocaine to Prevent Post-Fundal Pressure Headache During Cesarean Section

NCT07661758 · tracked via the Priya Life Science Egypt tracker
Sponsor
Tanta University
Phase
Phase 3
Started
2026-07-01
Last updated
2026-07-06

Condition(s) studied

Intravenous LidocaineFundal PressureHeadache

Investigational drug(s) / intervention(s)

Lidocaine IV →Saline 0.9%

Lidocaine IV: IV lidocaine 1.5 mg/kg (diluted with 0.9% isotonic saline to a total volume of 10 ml) over 5 minutes with the start of skin incision after ensuring negative baseline headache.

Saline 0.9%: IV 10 ml isotonic saline over 5 minutes with the start of skin incision after ensuring negative baseline headache.

Study summary

This prospective randomized controlled multicenter study will be conducted to evaluate the effects of pre-emptive IV lidocaine dose on the incidence and severity of intraoperative headache that may occur after the extra-abdominal manual uterine fundal pressure in patients undergoing cesarean section under spinal anesthesia.

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Aged ≥ 18 years * American Society of Anesthesiologists (ASA) Physical Status II * Scheduled for elective cesarean section under spinal anesthesia Exclusion Criteria: * Patients declined to participate in the trial, * Patients with history of any type of headache, mental illness, or cerebrovascular diseases * Previous epidural insertion for painless labor or any other indications; * Patients on opioid or analgesic medications; * Those with pregnancy-induced hypertension or diabetic patients, * Allergy to lidocaine; * Contraindication or failure of spinal anesthesia.

Primary outcome measure(s)

  • Incidence of intraoperative headache — Up to the end of surgery.
    The incidence of intraoperative headache that may occur after fundal pressure application until the end of surgery will be recorded.

Trial sites (1)

FacilityCityRegionStatus
Tanta University Hospitals Tanta Gharbia Governorate Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07661758 on ClinicalTrials.gov ↗ ← All trials in Egypt