Percutaneous Neurostimulation in Knee Osteoarthritis

NCT07637682 · tracked via the Priya Life Science Egypt tracker

Sponsor

Tanta University

Phase

Not applicable

Started

2026-06-02

Last updated

2026-06-18

Condition(s) studied

Osteoarthritis (OA) of the KneeNeuromodulation

Investigational drug(s) / intervention(s)

nerve stimulation using a nerve stimulator to the genicular nervenerve stimulation using a nerve stimulator to the saphenous nerve

nerve stimulation using a nerve stimulator to the genicular nerve: temporary transcutaneous nerve stimulation using a nerve stimulator to the genicular nerve, with settings 2Hz, 0.2mA, 1ms, where the nerve is stimulated for 4 to 6 minutes.

nerve stimulation using a nerve stimulator to the saphenous nerve: temporary transcutaneous nerve stimulation using a nerve stimulator to the saphenous nerve, with settings 2Hz, 0.2mA, 1ms, where the nerve is stimulated for 4 to 6 minutes.

Study summary

Peripheral nerve stimulation (PNS) is a drug-free pain management procedure that uses electrical impulses to target specific nerves and block pain signals. PNS helps decrease perception of pain, providing real answers to patients dealing with chronic knee pain. The case study discussed in this presentation is of the use of PNS targeting the superior lateral genicular nerve and the saphenous nerve for a patient with moderate to severe knee pain from osteoarthritis

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: 1. adults between the ages of 30 and 70 years with a clinical diagnosis of moderate to severe knee OA who suffered knee pain. 2. Patients who cannot afford intra-articular injections or radiofrequency ablation (RFA). 3. patients who had failed 2 different oral pain medications and 6 weeks of physical therapy. Exclusion Criteria: 1. Patients with OA show improvement in pain after physiotherapy. 2. patients evaluated by an orthopaedic surgeon and deemed to be surgical candidates due to knee pathologies other than OA. 3. pregnant patients. 4. patients on anticoagulation therapy, who were not permitted to stop anticoagulation. 5. patients with previous trauma, neurological or endocrine diseases like diabetes mellitus, and knee tumors; and patients with inflammatory arthritis. 6. people who had received an intra-articular knee injection within the last 6 months. 7. Patients with tendon tears, bursitis, or calcified tendonitis as proven by imaging.

Primary outcome measure(s)

Change in visual analogue scale after intervention. — immediately after intervention.
Decrement (clinical improvement) in visual analogue scale (VAS) immediately after intervention. The participant's knee discomfort was measured using a VAS. Participants were asked to score their level of pain on a 100-mm horizontal line, ranging from 0 to 100.

Trial sites (1)

Facility	City	Region	Status
Faculty of medicine, Tanta University	Tanta	Egypt	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07637682 on ClinicalTrials.gov ↗ ← All trials in Egypt