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Clinical Trials in Egypt / NCT07419191
Starting soon Observational

Role of Endoscopic Ultrasound Elastography in Diagnosis of Gastrointestinal Subepithelial and Mediastinal Lesions

NCT07419191 · tracked via the Priya Life Science Egypt tracker
Sponsor
Assiut University
Phase
Observational
Started
2026-02-08
Last updated
2026-02-18

Condition(s) studied

Mediastinal ( Chest) MassesGastrointestinal Subepithelial Tumors

Study summary

The aim of this study is to evaluate the role of endoscopic ultrasound (EUS) in the diagnosis of mediastinal and gastrointestinal subepithelial lesions.

The study also aims to assess the diagnostic accuracy of endoscopic ultrasound (EUS) elastography in differentiating benign from malignant mediastinal and gastrointestinal subepithelial lesions.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age: Adults ≥ 12 years. * Clinical indication: Patients referred for diagnostic EUS of a 1\_mediastinal mass or mediastinal lymphadenopathy detected on prior imaging (CT/MRI) . 2- subepithelial lesions lesion detected by endoscopy . * Lesion accessibility: Lesion judged by the endosonographer to be accessible to EUS imaging and elastography and amenable to EUS-guided sampling Exclusion Criteria: * • patient Refusal or inability to provide informed consent * Uncorrectable coagulation disorder * Presence of contraindicating endoscopy/sedation * Lesion inaccessible to EUS or elastography (e.g., too far from the esophagus/airway to obtain reliable elastography or visualization) as judged by the performing endosonographer.

Primary outcome measure(s)

  • Diagnostic yield of endoscopic ultrasound in mediastinal lesions and gastrointestinal subepithelial lesions — At time of diagnostic procedure and after histopathological confirmation (within 2 weeks)
    Diagnostic yield will be defined as the proportion of participants in whom endoscopic ultrasound provides a definitive diagnosis confirmed by histopathological examination obtained through fine-needle aspiration, fine-needle biopsy, or surgical specimens

Trial sites (1)

FacilityCityRegionStatus
Faculty of Medicine Asyut Asyut Governorate

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07419191 on ClinicalTrials.gov ↗ ← All trials in Egypt