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Clinical Trials in Egypt / NCT07356219
Active, not recruiting Observational

Prognostic Nutritional Index for Predicting Outcomes Following Coronary Artery Bypass Grafting (CABG) Surgery

NCT07356219 · tracked via the Priya Life Science Egypt tracker
Sponsor
Benha University
Phase
Observational
Started
2025-11-15
Last updated
2026-01-21

Condition(s) studied

Coronary Artery Disease

Investigational drug(s) / intervention(s)

Prognostic Nutritional Index (PNI)Neutrophil-to-Lymphocyte Ratio (NLR)Body Mass Index (BMI)

Prognostic Nutritional Index (PNI): Calculated using serum albumin (g/L) and total peripheral lymphocyte count.

Neutrophil-to-Lymphocyte Ratio (NLR): Calculated from peripheral blood counts.

Body Mass Index (BMI): Calculated from preoperative weight and height.

Study summary

Coronary artery bypass grafting (CABG) is a major cardiac surgery associated with risks of serious perioperative complications and mortality. Malnutrition and inflammation are known independent risk factors for poor outcomes in patients with coronary artery disease. This retrospective observational study evaluates the Prognostic Nutritional Index (PNI)-a simple score derived from serum albumin and lymphocyte counts-as an objective measure of nutritional and inflammatory status. The research aims to determine how well preoperative PNI and its postoperative changes can predict complications such as acute kidney injury, myocardial infarction, and sternal wound infections in patients undergoing CABG.

Eligibility

Sex
ALL
Min age
25 Years
Max age
55 Years
Healthy volunteers
No
Inclusion Criteria: * Patients who underwent CABG surgery. * Availability of a signed informed consent form before surgery. Exclusion Criteria: * Other concurrent cardiac surgeries. * Presence of malignancy or systemic inflammatory disorders. * Active infection or autoimmune disorders. * Maintenance on immunosuppressants. * Liver disease. * Files with missing data.

Primary outcome measure(s)

  • Diagnostic Accuracy of the Prognostic Nutritional Index (PNI) in Predicting Post-CABG Complications. — Approximately 30 days (From surgery through the duration of the hospital/ICU stay.)
    The Area Under the Receiver Operating Characteristic (ROC) Curve (AUC) used to determine the performance of the PNI score in predicting the occurrence of major postoperative complications.

Trial sites (1)

FacilityCityRegionStatus
Benha University Banhā Al Qalyoubia

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Other trials for the same condition

The Effect of Remote Ischemic Preconditioning on Diastolic Function in Coronary Artery Bypass Surgery Between Diabetic and Non-Diabetic Patients Active, not recruiting
EFFECT OF PYRAMIDAL TRAINING ON EPICARDIAL FAT FOR CORONARY ARTERY DISEASE PREVENTION Starting soon
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C) Recruiting
Prospective Global Registry for the Study of Chronic Total Occlusion Intervention Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07356219 on ClinicalTrials.gov ↗ ← All trials in Egypt