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Clinical Trials in Egypt / NCT07188688
Starting soon Observational

SWE to Detect Enthesitis in PsA: Relationship With SIRT2 Expression and Disease Activity

NCT07188688 · tracked via the Priya Life Science Egypt tracker
Sponsor
Assiut University
Phase
Observational
Started
2025-10
Last updated
2025-09-23

Condition(s) studied

Shear Wave Elastography

Investigational drug(s) / intervention(s)

Musculoskeletal Ultrasound Device

Musculoskeletal Ultrasound Device: Musculoskeletal Ultrasound assessment by LOGIQ P10 from General Electric (GE) Healthcare, each patient will be evaluated by grey scale, power doppler MSUS and Shear Wave Elastography (SWE)

Study summary

1. To assess the diagnostic utility of shear-wave elastography (SWE), gray-scale (GS) ultrasound, and Power Doppler (PD) in detecting Patellar and Achilles tendinopathy in psoriatic patients with and without arthritis.
2. Investigate the relation between SWE, GS ultrasound, and PD finding and SIRT2 expression levels.
3. Evaluate the association of the imaging findings and SIRT2 levels with psoriatic arthritis disease activity score.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients diagnosed as PsO by a dermatologist according to PASI score. * Patients diagnosed as PsA by rheumatologist according to CASPAR classification criteria for psoriatic arthritis * Adult patients of both sexes with an average \> 18 years Exclusion Criteria: * Patients with a history of metabolic disease affecting tendons. * Patients with history of surgery, injury or trauma of patellar and/or Achilles tendon. * Patients with other rheumatological diseases. * Patients below 18.

Primary outcome measure(s)

  • Assessment and comparting the diagnostic utility of shear-wave elastography (SWE) , Gray-scale (GS) ultrasound. and Power Doppler (PD) in detecting tendinopathy in psoriatic patients with and without arthritis. — At baseline (single study visit)
    Musculoskeletal Ultrasound assessment by LOGIQ P10 from General Electric (GE) Healthcare, a division of General Electric Company

Trial sites (1)

FacilityCityRegionStatus
Assiut University Asyut Egypt

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07188688 on ClinicalTrials.gov ↗ ← All trials in Egypt