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Recruiting Observational

Endocan and Copeptin Serum Levels in Preterm Neonates With Respiratory Distress Syndrome

NCT07154134 · tracked via the Priya Life Science Egypt tracker
Phase
Observational
Started
2025-07-10
Last updated
2025-09-04

Condition(s) studied

EndocanCopeptinSerumPreterm NeonatesRespiratory Distress Syndrome

Investigational drug(s) / intervention(s)

Serum endocanSerum copeptin

Serum endocan: Serum endocan will be measured by an enzyme-linked immunosorbent assay (ELISA) on the first day of life.

Serum copeptin: Serum copeptin will be measured by an enzyme-linked immunosorbent assay (ELISA) on the first day of life.

Study summary

This work aims to investigate and compare the levels of serum endocan and serum copeptin on the first day of life and correlate their levels to the severity of respiratory distress in preterm neonates suffering from respiratory distress syndrome.

Eligibility

Sex
ALL
Min age
28 Weeks
Max age
36 Weeks
Healthy volunteers
No
Inclusion Criteria: * Prematurity. * Gestational age between 28 and 36 weeks. * Suffering from respiratory distress syndrome. Exclusion Criteria: * Intrauterine growth restriction (IUGR). * Hypoxic ischemic encephalopathy. * Multiple congenital anomalies. * Chromosomal abnormalities. * Preterm less than 28 weeks. * Neonates with a maternal history of chorioamnionitis (early sepsis). * Infant of diabetic mother. * Prelabor rupture of membranes (PROM)\> 2 hours.

Primary outcome measure(s)

  • Serum endocan level for prediction of severity of respiratory distress syndrome — First day of life
    Serum endocan level for prediction of severity of respiratory distress syndrome (RDS) will be recorded.

Trial sites (1)

FacilityCityRegionStatus
Tanta University Tanta El-Gharbia Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07154134 on ClinicalTrials.gov ↗ ← All trials in Egypt