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Clinical Trials in Egypt / NCT07147270
Recruiting Not applicable

Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound

NCT07147270 · tracked via the Priya Life Science Egypt tracker
Sponsor
Ain Shams University
Phase
Not applicable
Started
2025-05-01
Last updated
2025-08-29

Condition(s) studied

Effect of Patient Rotation on Pleurodesis Success and Patient ComfortMalignant Pleural EffusionPleurodesis

Investigational drug(s) / intervention(s)

side to side and front to back rotation 30 minutes each

side to side and front to back rotation 30 minutes each: side to side and front to back rotation 30 minutes each after pleurodesis

Study summary

chemical pleurodesis using doxycycline is an acceptable and commonly employed palliation for malignant pleural effusion. Rotation of patient during pleurodesis using the powder from doxycycline capsule is still practiced in some centers. The benefit of rotation practice in pleurodesis can be verified after properly designed study on the outcome of pleurodesis with rotation and non-rotation by chest ultrasound assessment

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients who will be admitted at Chest department, Ain-Shams University Hospitals with malignant pleural effusions candidate for pleurodesis Exclusion Criteria: * Multiloculated fluid * Previous failed pleurodesis * Liver failure * Renal failure * Congestive heart failure * Prolonged use of steroids or NSAIDs * Refusal to participate

Primary outcome measure(s)

  • Measurement of pleural adhesion score in patients with malignant pleural effusion candidates for pleurodesis in group with rotation and the other without rotation — immediatly and after one month from pleurodesis
    study how patient rotation after pleurodesis affects its success by measuring pleural adherence score by chest ultrasound, a higher adhesion score means successful pleurodesis

Trial sites (1)

FacilityCityRegionStatus
Ain Shams university Cairo Egypt Recruiting

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Other trials for the same condition

Pleural Bleomycin vs Mechanical Abrasion in Malignant Pleural Effusion Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07147270 on ClinicalTrials.gov ↗ ← All trials in Egypt