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Clinical Trials in Egypt / NCT07113197
Starting soon Not applicable

Duplex Ultrasound Versus Conventional Angiography in Evaluating Lower Limb Threatening Ischemia

NCT07113197 · tracked via the Priya Life Science Egypt tracker
Sponsor
Sohag University
Phase
Not applicable
Started
2025-09-02
Last updated
2025-08-08

Condition(s) studied

Chronic Threatening Lower Limb Ischemia

Investigational drug(s) / intervention(s)

conventional angiography

conventional angiography: * Peak systolic velocity (PSV) * Velocity ratios * Segment visualization quality * Degree of stenosis

Study summary

This study aims to evaluate the accuracy of Duplex Ultrasound (DUS) in assessing infra inguinal arterial lesions in patients with chronic threatening limb ischemia compared with digital subtraction angiography (DSA) as the reference standard. By comparing sensitivity, specificity, and predictive values across arterial segments, the study seeks to determine the clinical utility of DUS as a non-invasive alternative for pre-intervention vascular mapping in chronic limb-threatening ischemia.

Eligibility

Sex
ALL
Min age
40 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: \- 1. Clinical diagnosis of chronic threatening lower limb ischemia (rest pain, non-healing ulcer, or gangrene). 2\. Ability to provide informed consent. Exclusion Criteria: * 1\. Hemodynamically unstable patients not fit for angiography. 2. Patients with non-atherosclerotic arterial diseases (e.g., vasculitis, Buerger's disease). 3\. Known contrast allergy or renal insufficiency precluding contrast angiography. 4\. Inadequate acoustic window or inability to undergo complete DUS examination.

Primary outcome measure(s)

  • Diagnostic accuracy of DUS compared to DSA in detecting ≥50% stenosis or occlusion in femoral, popliteal, and infra popliteal arteries. — from enrollment till angioplasty (14 days mostly)
    sensitivity, specificity, positive predictive value, negative predictive value

Trial sites (1)

FacilityCityRegionStatus
Sohag University Hospital Sohag Sohag Governorate

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07113197 on ClinicalTrials.gov ↗ ← All trials in Egypt