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Recruiting Observational

Diffusion Magnetic Resonance Imaging (dMRI) in the Early Evaluation of Brain White Matter Diseases

NCT07108712 · tracked via the Priya Life Science Egypt tracker
Phase
Observational
Started
2025-05-01
Last updated
2025-08-07

Condition(s) studied

Diffusion Magnetic Resonance ImagingBrain White Matter Diseases

Investigational drug(s) / intervention(s)

Magnetic Resonance Imaging (MRI)

Magnetic Resonance Imaging (MRI): Magnetic Resonance Imaging (MRI) Scanner: All imaging will be performed using a 1.5 tesla MRI scanner to ensure high resolution and signal-to-noise ratio.

Study summary

To assess the sensitivity and accuracy of diffusion magnetic resonance imaging (MRI), including diffusion-weighted imaging (DWI) metrics, in identifying early-stage changes in brain white matter related to various white matter diseases.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * Adults aged 18-80 years. * Clinical suspicion of early-stage white matter disease. * No prior diagnosis of significant neurological disorders (e.g., stroke, brain tumors). * Ability to provide informed consent. Exclusion Criteria: * Pregnancy or breastfeeding. * Contraindications for magnetic resonance imaging (MRI) (e.g., metal implants, pacemakers). * Severe psychiatric or cognitive impairment that prevents participation. * Control Group: Healthy individuals without any clinical history of neurological diseases, matched by age and sex to the patient cohort.

Primary outcome measure(s)

  • Sensitivity of diffusion magnetic resonance imaging — Immediately after diffusion magnetic resonance imaging (Up to 1 hour)
    Sensitivity of diffusion magnetic resonance imaging to predict the early evaluation of brain white matter diseases

Trial sites (1)

FacilityCityRegionStatus
General Authority for Teaching Hospitals and Institutes Cairo Egypt Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07108712 on ClinicalTrials.gov ↗ ← All trials in Egypt