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Clinical Trials in Egypt / NCT07076771
Recruiting Observational

Serum Testosterone Level on Angiographic Complexity of Coronary Lesions in Premature Ischemic Egyptian Males

NCT07076771 · tracked via the Priya Life Science Egypt tracker
Sponsor
Sohag University
Phase
Observational
Started
2025-01-01
Last updated
2025-07-22

Condition(s) studied

TestosteroneAngiographic ComplexityCoronary LesionPremature IschemiaMales

Investigational drug(s) / intervention(s)

Coronary AngiographySyntax Score

Coronary Angiography: All angiographic procedures will be performed. Coronary artery disease will be defined as \>70% stenosis in at least one major epicardial artery or \>50% the left main coronary artery.

Syntax Score: The angiographic complexity of coronary artery disease (CAD) will be assessed using the SYNTAX score.

Study summary

This study aims to investigate the association between serum testosterone levels and the angiographic complexity of coronary artery lesions in male patients under 45 years of age presenting with premature ischemic heart disease.

Eligibility

Sex
MALE
Min age
—
Max age
45 Years
Healthy volunteers
No
Inclusion Criteria: * Male patients aged \<45 years. * Diagnosed with premature ischemic heart disease. * Undergoing elective coronary angiography for suspected coronary artery disease (CAD) . Exclusion Criteria: * History of acute coronary syndrome within the preceding 3 months. * Prior diagnosis of hypogonadism or history of testosterone replacement therapy or anabolic steroid use. * Active neoplasm or history of chemotherapy. * Known hepatic cirrhosis, chronic kidney disease, or end-stage renal disease. * Use of medications known to affect sex hormone levels (e.g., spironolactone, ketoconazole). * Endocrine disorders such as sickle cell anemia or celiac disease.

Primary outcome measure(s)

  • Serum testosterone level — Immediately after angiography (Up to 1 hour)
    Serum testosterone level will be measured.

Trial sites (1)

FacilityCityRegionStatus
Sohag University Sohag Egypt Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07076771 on ClinicalTrials.gov ↗ ← All trials in Egypt