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Starting soon Not applicable

Antimicrobial Impact of Various RC Final Irrigation Activation Techniques

NCT07056127 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2025-08-01
Last updated
2025-07-09

Condition(s) studied

Root Canal Final Irrigation Activation Techniques

Investigational drug(s) / intervention(s)

manual dynamic agitaionultrasonic activationxp-endo finisherlaser

manual dynamic agitaion: 5 mL of 2.5% NaOCl solution will be activated with a well-fitting gutta-percha cone that will be placed to full working length and then will be moved in push-pull strokes of 2 mm amplitude at a frequency of 100 strokes in about 1 min

ultrasonic activation: 5 mL of 5.25% NaOCl solution will be activated with PUI using a #20 endosonic file that will be driven by an ultrasonic device on medium power setting for 1 minute and inserted 1 mm short of the working length

xp-endo finisher: 5 mL of 5.25% NaOCl solution will be activated with XP-Endo Finisher which will be used in the canal for 1 minute at 800 rpm and 1 Ncm up to the working length and in slow up-and-down movements at 7-8mm length according to the manufacturer's recommendations

laser: First, root canals will be filled with 0.5 mL of 0.05% ICG dye and left in place for 1 minute as preirradiation time. A #20 laser fiber will be inserted into the root canals to the working length. Then infrared diode laser with a wave length of 810 nm will be used to activate the dye for 30 seconds. For activation, circular movements will be performed along with the fiber removal movement . After the first activation, dye will be reintroduced, the laser fiber will be inserted again, and a new activation cycle of 30 seconds will be performed similarly to the previous one

Study summary

This randomized clinical study aims to evaluate microbial reduction in root canals after using different final irrigation activation techniques including passive ultrasonic irrigation, XP-endo Finisher file and Laser ablation with Indocyanine green dye in comparison to manual dynamic activation.

Eligibility

Sex
ALL
Min age
15 Years
Max age
45 Years
Healthy volunteers
No
Inclusion Criteria: • Vital/non vital single rooted teeth with single root canal with nearly the same apical diameter requiring root canal treatment. * Teeth with sound periodontal apparatus. Exclusion Criteria: * • Teeth with anatomic anomilies. * Retreatment cases * Pregnant patients

Primary outcome measure(s)

  • bacterial count — 24-48 hours

Trial sites (1)

FacilityCityRegionStatus
Faculty of dentistry Tanta Egypt
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07056127 on ClinicalTrials.gov ↗ ← All trials in Egypt