Lingual Ondansetron in Reduction of Spinal Hypotension in Cesarean Section

Condition(s) studied

Investigational drug(s) / intervention(s)

ondansetron lingual film: 8 mg of the lingual film form of ondansetron, given 15 minutes before spinal anesthesia

Placebo: a placebo lingual film form, given 15 minutes before spinal anesthesia

Study summary

The goal of this clinical trial is to learn if drug ondansetron, used in lingual form, lowers the incidence of spinal anesthesia-induced hypotension in cesarean sections. It will also learn about the safety of drug ondansetron. The main questions it aims to answer are

Does the drug ondansetron, used in lingual form, lower the incidence of spinal anesthesia-induced hypotension in cesarean sections? What medical problems do participants have when taking the drug ondansetron? Researchers will compare drug ondansetron to a placebo (a look-alike substance that contains no drug) to see if drug ondansetron works to reduce the incidence of spinal anesthesia-induced hypotension in cesarean sections

Participants will:

Take drug ondansetron or a placebo before induction of spinal anesthesia

Eligibility

Primary outcome measure(s)

• ephidrine consumption — From the moment the surgery starts until it is finished, or after 90 minutes has passed, whichever is longer
  To evaluate the impact of lingual ondansetron on parturients having cesarean sections' overall intraoperative ephedrine consumption

Trial sites (1)

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